7P34

Cryo-EM structure of the proton-dependent antibacterial peptide transporter SbmA-FabS11-1 in nanodiscs

Summary for 7P34

• Entry DOI: 10.2210/pdb7p34/pdb
• EMDB information: 13168
• Descriptor: Peptide antibiotic transporter SbmA, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate (2 entities in total)
• Functional Keywords: slipt, proton transport, peptide transport, antibiotics, transport protein
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 94490.09

Authors

Ghilarov, D.,Beis, K. (deposition date: 2021-07-07, release date: 2021-09-15, Last modification date: 2024-07-17)

• Primary citation: Ghilarov, D.,Inaba-Inoue, S.,Stepien, P.,Qu, F.,Michalczyk, E.,Pakosz, Z.,Nomura, N.,Ogasawara, S.,Walker, G.C.,Rebuffat, S.,Iwata, S.,Heddle, J.G.,Beis, K.; Molecular mechanism of SbmA, a promiscuous transporter exploited by antimicrobial peptides.; Sci Adv, 7:eabj5363-eabj5363, 2021; PubMed: 34516884; DOI: 10.1126/sciadv.abj5363

Experimental method

ELECTRON MICROSCOPY (3.59 Å)