7P1E
Structure of KDNase from Aspergillus Terrerus in complex with 2,3-difluoro-2-keto-3-deoxynononic acid
Summary for 7P1E
Entry DOI | 10.2210/pdb7p1e/pdb |
Descriptor | Sialidase domain-containing protein, 3-deoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, (2R,3R,4R,5R,6S)-2,3-bis(fluoranyl)-4,5-bis(oxidanyl)-6-[(1R,2R)-1,2,3-tris(oxidanyl)propyl]oxane-2-carboxylic acid, ... (7 entities in total) |
Functional Keywords | carbohydrate metabolism, enzyme structure, protein structure, kdn, kdnase, sialic acid, sialidase, carbohydrate |
Biological source | Aspergillus terreus (strain NIH 2624 / FGSC A1156) |
Total number of polymer chains | 1 |
Total formula weight | 45436.16 |
Authors | Gloster, T.M.,McMahon, S.A. (deposition date: 2021-07-01, release date: 2021-10-20, Last modification date: 2024-01-31) |
Primary citation | Nejatie, A.,Steves, E.,Gauthier, N.,Baker, J.,Nesbitt, J.,McMahon, S.A.,Oehler, V.,Thornton, N.J.,Noyovitz, B.,Khazaei, K.,Byers, B.W.,Zandberg, W.F.,Gloster, T.M.,Moore, M.M.,Bennet, A.J. Kinetic and Structural Characterization of Sialidases (Kdnases) from Ascomycete Fungal Pathogens. Acs Chem.Biol., 16:2632-2640, 2021 Cited by PubMed: 34724608DOI: 10.1021/acschembio.1c00666 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.53 Å) |
Structure validation
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