7P1E

Structure of KDNase from Aspergillus Terrerus in complex with 2,3-difluoro-2-keto-3-deoxynononic acid

7P1E の概要

• エントリーDOI: 10.2210/pdb7p1e/pdb
• 分子名称: Sialidase domain-containing protein, 3-deoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, (2R,3R,4R,5R,6S)-2,3-bis(fluoranyl)-4,5-bis(oxidanyl)-6-[(1R,2R)-1,2,3-tris(oxidanyl)propyl]oxane-2-carboxylic acid, ... (7 entities in total)
• 機能のキーワード: carbohydrate metabolism, enzyme structure, protein structure, kdn, kdnase, sialic acid, sialidase, carbohydrate
• 由来する生物種: Aspergillus terreus (strain NIH 2624 / FGSC A1156)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45436.16

構造登録者

Gloster, T.M.,McMahon, S.A. (登録日: 2021-07-01, 公開日: 2021-10-20, 最終更新日: 2024-01-31)

• 主引用文献: Nejatie, A.,Steves, E.,Gauthier, N.,Baker, J.,Nesbitt, J.,McMahon, S.A.,Oehler, V.,Thornton, N.J.,Noyovitz, B.,Khazaei, K.,Byers, B.W.,Zandberg, W.F.,Gloster, T.M.,Moore, M.M.,Bennet, A.J.; Kinetic and Structural Characterization of Sialidases (Kdnases) from Ascomycete Fungal Pathogens.; Acs Chem.Biol., 16:2632-2640, 2021; PubMed: 34724608; DOI: 10.1021/acschembio.1c00666

実験手法

X-RAY DIFFRACTION (1.53 Å)