7OZX

Structure of human galactokinase 1 bound with azepan-1-yl(2,6-difluorophenyl)methanone

Summary for 7OZX

• Entry DOI: 10.2210/pdb7ozx/pdb
• Descriptor: Galactokinase, beta-D-galactopyranose, 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, ... (5 entities in total)
• Functional Keywords: galactokinase 1, galk1, fragment screen, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 174482.14

Authors

Mackinnon, S.R.,Bezerra, G.A.,Zhang, M.,Foster, W.,Krojer, T.,Brandao-Neto, J.,Arrowsmith, C.,Edwards, A.,Bountra, C.,Brennan, P.,Lai, K.,Yue, W.W. (deposition date: 2021-06-29, release date: 2022-05-25, Last modification date: 2024-01-31)

• Primary citation: Mackinnon, S.R.,Bezerra, G.A.,Zhang, M.,Foster, W.,Krojer, T.,Brandao-Neto, J.,Arrowsmith, C.,Edwards, A.,Bountra, C.,Brennan, P.,Lai, K.,Yue, W.W.; Structure of human galactokinase 1 bound with azepan-1-yl(2,6-difluorophenyl)methanone; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)