7OYJ

Crystal structure of hTEAD2 in complex with fragment at the interface 2

Summary for 7OYJ

Entry DOI	10.2210/pdb7oyj/pdb
Descriptor	Transcriptional enhancer factor TEF-4, PALMITIC ACID, 3-(1~{H}-pyrazol-5-yl)aniline, ... (4 entities in total)
Functional Keywords	tead, fragment, transcription
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	55650.23
Authors	Guichou, J.F.,Gelin, M.,Allemand, F. (deposition date: 2021-06-24, release date: 2022-05-25, Last modification date: 2024-01-31)
Primary citation	Liberelle, M.,Toulotte, F.,Renault, N.,Gelin, M.,Allemand, F.,Melnyk, P.,Guichou, J.F.,Cotelle, P. Toward the Design of Ligands Selective for the C-Terminal Domain of TEADs. J.Med.Chem., 65:5926-5940, 2022 Cited by PubMed: 35389210 DOI: 10.1021/acs.jmedchem.2c00075 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.91 Å)

Structure validation