7OY0
Structure of human Spermine Oxidase in complex with a highly selective allosteric inhibitor
Summary for 7OY0
Entry DOI | 10.2210/pdb7oy0/pdb |
Descriptor | Spermine oxidase,Spermine oxidase,Spermine oxidase, FAD-MDL72527 adduct, 4-[(4-imidazo[1,2-a]pyridin-3-yl-1,3-thiazol-2-yl)amino]phenol, ... (5 entities in total) |
Functional Keywords | spermine oxidase, polyamine metabolism, spermine, spermidine, inhibitor, unknown function |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 56173.36 |
Authors | Impagliazzo, A.,Thomsen, M.,Johannsson, S.,Krapp, S. (deposition date: 2021-06-23, release date: 2022-07-13, Last modification date: 2022-08-17) |
Primary citation | Diaz, E.,Adhikary, S.,Tepper, A.W.J.W.,Riley, D.,Ortiz-Meoz, R.,Krosky, D.,Buyck, C.,Lamenca, C.M.,Llaveria, J.,Fang, L.,Kalin, J.H.,Klaren, V.N.A.,Fahmy, S.,Shaffer, P.L.,Kirkpatrick, R.,Carbajo, R.J.,Thomsen, M.,Impagliazzo, A. Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor. Commun Biol, 5:787-787, 2022 Cited by PubMed: 35931745DOI: 10.1038/s42003-022-03735-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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