7OY0

Structure of human Spermine Oxidase in complex with a highly selective allosteric inhibitor

7OY0 の概要

• エントリーDOI: 10.2210/pdb7oy0/pdb
• 分子名称: Spermine oxidase,Spermine oxidase,Spermine oxidase, FAD-MDL72527 adduct, 4-[(4-imidazo[1,2-a]pyridin-3-yl-1,3-thiazol-2-yl)amino]phenol, ... (5 entities in total)
• 機能のキーワード: spermine oxidase, polyamine metabolism, spermine, spermidine, inhibitor, unknown function
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 56173.36

構造登録者

Impagliazzo, A.,Thomsen, M.,Johannsson, S.,Krapp, S. (登録日: 2021-06-23, 公開日: 2022-07-13, 最終更新日: 2022-08-17)

• 主引用文献: Diaz, E.,Adhikary, S.,Tepper, A.W.J.W.,Riley, D.,Ortiz-Meoz, R.,Krosky, D.,Buyck, C.,Lamenca, C.M.,Llaveria, J.,Fang, L.,Kalin, J.H.,Klaren, V.N.A.,Fahmy, S.,Shaffer, P.L.,Kirkpatrick, R.,Carbajo, R.J.,Thomsen, M.,Impagliazzo, A.; Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor.; Commun Biol, 5:787-787, 2022; PubMed: 35931745; DOI: 10.1038/s42003-022-03735-9

実験手法

X-RAY DIFFRACTION (2.09 Å)