7OVT
major seeded in vitro fibril morphology from murine SAA1.1 protein
Summary for 7OVT
Entry DOI | 10.2210/pdb7ovt/pdb |
EMDB information | 13089 8910 |
Descriptor | Serum amyloid A-2 protein (1 entity in total) |
Functional Keywords | systemic amyloidosis, seeded, misfolding disease, inflammation, prion, protein fibril |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 12 |
Total formula weight | 139471.55 |
Authors | Heerde, T.,Schmidt, M.,Faendrich, M. (deposition date: 2021-06-15, release date: 2022-02-02, Last modification date: 2024-07-17) |
Primary citation | Heerde, T.,Rennegarbe, M.,Biedermann, A.,Savran, D.,Pfeiffer, P.B.,Hitzenberger, M.,Baur, J.,Puscalau-Girtu, I.,Zacharias, M.,Schwierz, N.,Haupt, C.,Schmidt, M.,Fandrich, M. Cryo-EM demonstrates the in vitro proliferation of an ex vivo amyloid fibril morphology by seeding. Nat Commun, 13:85-85, 2022 Cited by PubMed: 35013242DOI: 10.1038/s41467-021-27688-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.69 Å) |
Structure validation
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