7OTU
Human OMPD-domain of UMPS in complex with 6-hydroxy-UMP at 0.95 Angstroms resolution, crystal 2
Summary for 7OTU
Entry DOI | 10.2210/pdb7otu/pdb |
Descriptor | Isoform 2 of Uridine 5'-monophosphate synthase, 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, ... (4 entities in total) |
Functional Keywords | ompd, bmp, umps, orotidine 5'-monophosphate decarboxylase, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 28856.18 |
Authors | Rindfleisch, S.,Rabe von Pappenheim, F.,Tittmann, K. (deposition date: 2021-06-10, release date: 2022-04-20, Last modification date: 2024-01-31) |
Primary citation | Rindfleisch, S.,Krull, M.,Uranga, J.,Schmidt, T.,Rabe von Pappenheim, F.,Kirck, L.L.,Balouri, A.,Schneider, T.,Chari, A.,Kluger, R.,Bourenkov, G.,Diederichsen, U.,Mata, R.A.,Tittmann, K. Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis Nat Catal, 5:332-341, 2022 Cited by DOI: 10.1038/s41929-022-00771-wPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (0.95 Å) |
Structure validation
Download full validation report