7OTU

Human OMPD-domain of UMPS in complex with 6-hydroxy-UMP at 0.95 Angstroms resolution, crystal 2

7OTU の概要

• エントリーDOI: 10.2210/pdb7otu/pdb
• 分子名称: Isoform 2 of Uridine 5'-monophosphate synthase, 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: ompd, bmp, umps, orotidine 5'-monophosphate decarboxylase, lyase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28856.18

構造登録者

Rindfleisch, S.,Rabe von Pappenheim, F.,Tittmann, K. (登録日: 2021-06-10, 公開日: 2022-04-20, 最終更新日: 2024-01-31)

• 主引用文献: Rindfleisch, S.,Krull, M.,Uranga, J.,Schmidt, T.,Rabe von Pappenheim, F.,Kirck, L.L.,Balouri, A.,Schneider, T.,Chari, A.,Kluger, R.,Bourenkov, G.,Diederichsen, U.,Mata, R.A.,Tittmann, K.; Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis; Nat Catal, 5:332-341, 2022; DOI: 10.1038/s41929-022-00771-w

実験手法

X-RAY DIFFRACTION (0.95 Å)