7ORG
Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ162
Summary for 7ORG
| Entry DOI | 10.2210/pdb7org/pdb |
| Descriptor | 14-3-3 protein sigma, Cyclin-dependent kinase inhibitor 1B, ~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]-2,3-dihydro-1-benzofuran-7-carboxamide, ... (6 entities in total) |
| Functional Keywords | protein-peptide complex small-molecule, signaling protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 30588.21 |
| Authors | Centorrino, F.,Wu, Q.,Ottmann, C. (deposition date: 2021-06-05, release date: 2022-06-22, Last modification date: 2024-10-16) |
| Primary citation | Centorrino, F.,Wu, Q.,Cossar, P.,Brunsveld, L.,Ottmann, C. A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published, |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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