7OQ7
Ternary complex of 14-3-3 sigma, Estrogen Receptor alfa phosphopeptide, and WQ162
Summary for 7OQ7
Entry DOI | 10.2210/pdb7oq7/pdb |
Descriptor | 14-3-3 protein sigma, Estrogen receptor, ~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]-2,3-dihydro-1-benzofuran-7-carboxamide, ... (7 entities in total) |
Functional Keywords | protein-peptide complex small-molecule, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 30854.43 |
Authors | Centorrino, F.,Ottmann, C. (deposition date: 2021-06-02, release date: 2022-06-22, Last modification date: 2024-01-31) |
Primary citation | Centorrino, F.,Wu, Q.,Cossar, P.,Brunsveld, L.,Ottmann, C. A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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