7OOZ

Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 6-benzyloxo-2-chloropurine

Summary for 7OOZ

Entry DOI	10.2210/pdb7ooz/pdb
Descriptor	Purine nucleoside phosphorylase DeoD-type, GLYCEROL, MAGNESIUM ION, ... (7 entities in total)
Functional Keywords	inhibitor, complex, transferase
Biological source	Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Total number of polymer chains	2
Total formula weight	53796.00
Authors	Narczyk, M.,Stefanic, Z. (deposition date: 2021-05-28, release date: 2022-05-04, Last modification date: 2024-01-31)
Primary citation	Narczyk, M.,Wojtys, M.I.,Lescic Asler, I.,Zinic, B.,Luic, M.,Jagusztyn-Krynicka, E.K.,Stefanic, Z.,Bzowska, A. Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium. J Enzyme Inhib Med Chem, 37:1083-1097, 2022 Cited by PubMed: 35437103 DOI: 10.1080/14756366.2022.2061965 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation