7OOY

Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 6-benzylthio-2-chloropurine

7OOY の概要

• エントリーDOI: 10.2210/pdb7ooy/pdb
• 分子名称: Purine nucleoside phosphorylase DeoD-type, GLYCEROL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (6 entities in total)
• 機能のキーワード: inhibitor, complex, transferase
• 由来する生物種: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52774.73

構造登録者

Narczyk, M.,Stefanic, Z. (登録日: 2021-05-28, 公開日: 2022-05-04, 最終更新日: 2024-01-31)

• 主引用文献: Narczyk, M.,Wojtys, M.I.,Lescic Asler, I.,Zinic, B.,Luic, M.,Jagusztyn-Krynicka, E.K.,Stefanic, Z.,Bzowska, A.; Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium.; J Enzyme Inhib Med Chem, 37:1083-1097, 2022; PubMed: 35437103; DOI: 10.1080/14756366.2022.2061965

実験手法

X-RAY DIFFRACTION (1.9 Å)