7OND

HaloTag Engineering for Enhanced Fluorogenicity and Kinetics with a Styrylpyridine Dye

7OND の概要

• エントリーDOI: 10.2210/pdb7ond/pdb
• 分子名称: Haloalkane dehalogenase, 4-[(E)-2-[1-(7-chloranylheptyl)pyridin-1-ium-4-yl]ethenyl]-N,N-dimethyl-aniline, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: halotag, fluorescence, imaging, mammalian cells, fluorescent reporter, channel dye, directed evolution, fluorescent protein
• 由来する生物種: Rhodococcus sp.
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 69643.57

構造登録者

Stein, A.,Liang, A.D. (登録日: 2021-05-25, 公開日: 2021-07-21, 最終更新日: 2024-01-31)

• 主引用文献: Miro-Vinyals, C.,Stein, A.,Fischer, S.,Ward, T.R.,Deliz Liang, A.; HaloTag Engineering for Enhanced Fluorogenicity and Kinetics with a Styrylpyridium Dye.; Chembiochem, 22:3398-3401, 2021; PubMed: 34609782; DOI: 10.1002/cbic.202100424

実験手法

X-RAY DIFFRACTION (1.45 Å)