7ON0

Thermus sp. 2.9 DarT in complex with ADP-ribosylated ssDNA

This is a non-PDB format compatible entry.

Summary for 7ON0

• Entry DOI: 10.2210/pdb7on0/pdb
• Descriptor: DarT domain-containing protein, DNA (5'-D(*AP*TP*GP*TP*C)-3'), [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, ... (4 entities in total)
• Functional Keywords: toxin-antitoxin, dna adp-ribosylation, adp-ribosyltransferase activity, dna binding, toxin
• Biological source: Thermus sp. 2.9; More
• Total number of polymer chains: 2
• Total formula weight: 26491.51

Authors

Schuller, M.,Ariza, A. (deposition date: 2021-05-24, release date: 2021-06-23, Last modification date: 2024-05-01)

• Primary citation: Schuller, M.,Butler, R.E.,Ariza, A.,Tromans-Coia, C.,Jankevicius, G.,Claridge, T.D.W.,Kendall, S.L.,Goh, S.,Stewart, G.R.,Ahel, I.; Molecular basis for DarT ADP-ribosylation of a DNA base.; Nature, 596:597-602, 2021; PubMed: 34408320; DOI: 10.1038/s41586-021-03825-4

Experimental method

X-RAY DIFFRACTION (1.46 Å)