7O9R

Crystal structure of holo-H44A mutant of Hydroxy ketone aldolase (SwHKA) from Sphingomonas wittichii RW1

This is a non-PDB format compatible entry.

Summary for 7O9R

• Entry DOI: 10.2210/pdb7o9r/pdb
• Related: 6R62 7NNK 7NR1 7NUJ 7O5I 7O5R 7O5V 7O5W 7O87
• Descriptor: HpcH/HpaI aldolase, MAGNESIUM ION, POTASSIUM ION, ... (6 entities in total)
• Functional Keywords: class ii pyruvate aldolase, metal dependent, aldol reaction, magnesium, carbon bond formation, holo, lyase
• Biological source: Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)
• Total number of polymer chains: 2
• Total formula weight: 54186.36

Authors

Laustsen, J.,Justo, I.,Marsden, S.R.,Hanefeld, U.,Bento, I. (deposition date: 2021-04-16, release date: 2022-10-26, Last modification date: 2024-01-31)

• Primary citation: Marsden, S.R.,Wijma, H.J.,Mohr, M.K.F.,Justo, I.,Hagedoorn, P.L.,Laustsen, J.,Jeffries, C.M.,Svergun, D.,Mestrom, L.,McMillan, D.G.G.,Bento, I.,Hanefeld, U.; Substrate Induced Movement of the Metal Cofactor between Active and Resting State.; Angew.Chem.Int.Ed.Engl., 61:e202213338-e202213338, 2022; PubMed: 36214476; DOI: 10.1002/anie.202213338

Experimental method

X-RAY DIFFRACTION (1.85 Å)