7O28

Crystal structure of the human METTL3-METTL14 complex bound to Compound 19 (ADO_AE_009)

7O28 の概要

• エントリーDOI: 10.2210/pdb7o28/pdb
• 分子名称: N6-adenosine-methyltransferase catalytic subunit, N6-adenosine-methyltransferase non-catalytic subunit, 9-(2-chloranyl-7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl)-4-[4-[(4,4-dimethylpiperidin-1-yl)methyl]phenyl]-1,4,9-triazaspiro[5.5]undecan-2-one, ... (5 entities in total)
• 機能のキーワード: mettl3, inhibitor, complex, transferase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 62346.46

構造登録者

Bedi, R.K.,Dolbois, A.,Caflisch, A. (登録日: 2021-03-30, 公開日: 2021-09-15, 最終更新日: 2024-11-20)

• 主引用文献: Bedi, R.K.,Dolbois, A.,Caflisch, A.; Crystal structure of the human METTL3-METTL14 complex bound to Compound 19 (ADO_AE_009); To Be Published,

実験手法

X-RAY DIFFRACTION (2.47 Å)