7O22
X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 4 (mi359)
Summary for 7O22
Entry DOI | 10.2210/pdb7o22/pdb |
Descriptor | Furin, CALCIUM ION, SODIUM ION, ... (8 entities in total) |
Functional Keywords | proprotein convertase, inhibitor, sars-cov-2, protease, complex, furin, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 53151.49 |
Authors | Dahms, S.O.,Brandstetter, H. (deposition date: 2021-03-30, release date: 2021-09-01, Last modification date: 2024-01-31) |
Primary citation | Dahms, S.O.,Haider, T.,Klebe, G.,Steinmetzer, T.,Brandstetter, H. OFF-State-Specific Inhibition of the Proprotein Convertase Furin. Acs Chem.Biol., 16:1692-1700, 2021 Cited by PubMed: 34415722DOI: 10.1021/acschembio.1c00411 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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