7NZH
Crystal structure of HLA-DR4 in complex with a citrullinated cilp peptide
This is a non-PDB format compatible entry.
Summary for 7NZH
Entry DOI | 10.2210/pdb7nzh/pdb |
Descriptor | HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DR beta chain, citrullinated cartilage intermediate layer protein (CILP) peptide 982-996, ... (5 entities in total) |
Functional Keywords | complex, mhcii, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 91154.77 |
Authors | Ge, C.,Holmdahl, R. (deposition date: 2021-03-24, release date: 2022-05-11, Last modification date: 2024-01-31) |
Primary citation | Ge, C.,Weisse, S.,Xu, B.,Dobritzsch, D.,Viljanen, J.,Kihlberg, J.,Do, N.N.,Schneider, N.,Lanig, H.,Holmdahl, R.,Burkhardt, H. Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor. Ann Rheum Dis, 81:480-489, 2022 Cited by PubMed: 35027402DOI: 10.1136/annrheumdis-2021-220500 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.831 Å) |
Structure validation
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