7NX6
Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-222 and EY6A Fabs
Summary for 7NX6
Entry DOI | 10.2210/pdb7nx6/pdb |
Descriptor | EY6A Fab heavy chain, EY6A Fab light chain, Spike protein S1, ... (10 entities in total) |
Functional Keywords | sars-cov-2 b.1.1.7 variant, b.1.351 variant, p.1 variant, antibody, receptor-binding-domain, spike, neutralisation, viral protein/immune system, viral protein, immune system, viral protein-immune system complex |
Biological source | Homo sapiens More |
Total number of polymer chains | 5 |
Total formula weight | 119308.35 |
Authors | Zhou, D.,Ren, J.,Stuart, D. (deposition date: 2021-03-17, release date: 2021-04-07, Last modification date: 2024-01-31) |
Primary citation | Dejnirattisai, W.,Zhou, D.,Supasa, P.,Liu, C.,Mentzer, A.J.,Ginn, H.M.,Zhao, Y.,Duyvesteyn, H.M.E.,Tuekprakhon, A.,Nutalai, R.,Wang, B.,Lopez-Camacho, C.,Slon-Campos, J.,Walter, T.S.,Skelly, D.,Costa Clemens, S.A.,Naveca, F.G.,Nascimento, V.,Nascimento, F.,Fernandes da Costa, C.,Resende, P.C.,Pauvolid-Correa, A.,Siqueira, M.M.,Dold, C.,Levin, R.,Dong, T.,Pollard, A.J.,Knight, J.C.,Crook, D.,Lambe, T.,Clutterbuck, E.,Bibi, S.,Flaxman, A.,Bittaye, M.,Belij-Rammerstorfer, S.,Gilbert, S.C.,Carroll, M.W.,Klenerman, P.,Barnes, E.,Dunachie, S.J.,Paterson, N.G.,Williams, M.A.,Hall, D.R.,Hulswit, R.J.G.,Bowden, T.A.,Fry, E.E.,Mongkolsapaya, J.,Ren, J.,Stuart, D.I.,Screaton, G.R. Antibody evasion by the P.1 strain of SARS-CoV-2. Cell, 184:2939-, 2021 Cited by PubMed: 33852911DOI: 10.1016/j.cell.2021.03.055 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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