7NU3

Crystal Structure of Neisseria gonorrhoeae LeuRS E169G mutant in Complex with ATP and L-leucinol

Summary for 7NU3

• Entry DOI: 10.2210/pdb7nu3/pdb
• Related: 7NU2
• Descriptor: Leucine--tRNA ligase, 1,2-ETHANEDIOL, 2-AMINO-4-METHYL-PENTAN-1-OL, ... (7 entities in total)
• Functional Keywords: protein-ligand complex, rossmann fold, trna synthetase, ligase
• Biological source: Neisseria gonorrhoeae
• Total number of polymer chains: 1
• Total formula weight: 99396.61

Authors

Pang, L.,Strelkov, S.V.,Weeks, S.D. (deposition date: 2021-03-11, release date: 2022-08-31, Last modification date: 2024-01-31)

• Primary citation: Pang, L.,Zanki, V.,Strelkov, S.V.,Van Aerschot, A.,Gruic-Sovulj, I.,Weeks, S.D.; Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip.; Commun Biol, 5:883-883, 2022; PubMed: 36038645; DOI: 10.1038/s42003-022-03825-8

Experimental method

X-RAY DIFFRACTION (2.27 Å)