7NRX
Straight filament from Alzheimer's disease with PET ligand APN-1607
Summary for 7NRX
Entry DOI | 10.2210/pdb7nrx/pdb |
EMDB information | 12552 |
Descriptor | Microtubule-associated protein tau (1 entity in total) |
Functional Keywords | tau filament, protein fibril, positron emission tomography |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 10 |
Total formula weight | 459198.71 |
Authors | Shi, Y.,Murzin, A.G.,Falcon, B.,Epstein, A.,Machin, J.,Tempest, P.,Newell, K.L.,Vidal, R.,Garringer, H.J.,Sahara, N.,Higuchi, M.,Ghetti, B.,Jang, M.,Scheres, S.H.W.,Goedert, M. (deposition date: 2021-03-04, release date: 2021-03-24, Last modification date: 2024-07-10) |
Primary citation | Shi, Y.,Murzin, A.G.,Falcon, B.,Epstein, A.,Machin, J.,Tempest, P.,Newell, K.L.,Vidal, R.,Garringer, H.J.,Sahara, N.,Higuchi, M.,Ghetti, B.,Jang, M.K.,Scheres, S.H.W.,Goedert, M. Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607. Acta Neuropathol, 141:697-708, 2021 Cited by PubMed: 33723967DOI: 10.1007/s00401-021-02294-3 PDB entries with the same primary citation |
Experimental method |
Structure validation
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