7NLU

Crystal structure of Mycobacterium tuberculosis ArgB in complex with 1-(1H-indol-3-yl)ethan-1-one

Summary for 7NLU

Entry DOI	10.2210/pdb7nlu/pdb
Descriptor	Acetylglutamate kinase, SULFATE ION, 1-(1~{H}-indol-3-yl)ethanone, ... (4 entities in total)
Functional Keywords	argb acetylglutamate kinase, transferase
Biological source	Mycobacterium tuberculosis H37Rv
Total number of polymer chains	1
Total formula weight	31564.27
Authors	Mendes, V.,Thomas, S.E.,Cory-Wright, J.,Blundell, T.L. (deposition date: 2021-02-22, release date: 2021-06-30, Last modification date: 2024-01-31)
Primary citation	Gupta, P.,Thomas, S.E.,Zaidan, S.A.,Pasillas, M.A.,Cory-Wright, J.,Sebastian-Perez, V.,Burgess, A.,Cattermole, E.,Meghir, C.,Abell, C.,Coyne, A.G.,Jacobs, W.R.,Blundell, T.L.,Tiwari, S.,Mendes, V. A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19:3491-3506, 2021 Cited by DOI: 10.1016/j.csbj.2021.06.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.235 Å)

Structure validation