7NLN

Crystal structure of Mycobacterium tuberculosis ArgB in complex with N-acetyl-glutamate

7NLN の概要

• エントリーDOI: 10.2210/pdb7nln/pdb
• 分子名称: Acetylglutamate kinase, N-ACETYL-L-GLUTAMATE, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: argb acetylglutamate kinase, transferase
• 由来する生物種: Mycobacterium tuberculosis H37Rv
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 62990.46

構造登録者

Mendes, V.,Thomas, S.E.,Cory-Wright, J.,Blundell, T.L. (登録日: 2021-02-22, 公開日: 2021-06-30, 最終更新日: 2024-01-31)

• 主引用文献: Gupta, P.,Thomas, S.E.,Zaidan, S.A.,Pasillas, M.A.,Cory-Wright, J.,Sebastian-Perez, V.,Burgess, A.,Cattermole, E.,Meghir, C.,Abell, C.,Coyne, A.G.,Jacobs, W.R.,Blundell, T.L.,Tiwari, S.,Mendes, V.; A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis; Comput Struct Biotechnol J, 19:3491-3506, 2021; DOI: 10.1016/j.csbj.2021.06.006

実験手法

X-RAY DIFFRACTION (1.92 Å)