7NL5

Structure of the catalytic domain of the Bacillus circulans alpha-1,6 Mannanase in complex with an alpha-1,6-alpha-manno-cyclophellitol trisaccharide inhibitor

7NL5 の概要

• エントリーDOI: 10.2210/pdb7nl5/pdb
• 分子名称: Alpha-1,6-mannanase, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose, (1R,6S)-5beta-(Hydroxymethyl)-7-oxabicyclo[4.1.0]heptane-2beta,3beta,4alpha-triol, ... (5 entities in total)
• 機能のキーワード: mannanase, cyclophellitol, epoxide, hydrolase
• 由来する生物種: Bacillus circulans
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41627.51

構造登録者

Schroeder, S.,Offen, W.A.,Males, A.,Jin, Y.,De Boer, C.,Enotarpi, J.,Marino, L.,van der Marel, G.A.,Florea, B.I.,Codee, J.D.C.,Overkleeft, H.S.,Davies, G.J. (登録日: 2021-02-22, 公開日: 2021-04-28, 最終更新日: 2024-01-31)

• 主引用文献: Schroder, S.P.,Offen, W.A.,Males, A.,Jin, Y.,de Boer, C.,Enotarpi, J.,Marino, L.,van der Marel, G.A.,Florea, B.I.,Codee, J.D.C.,Overkleeft, H.S.,Davies, G.J.; Development of Non-Hydrolysable Oligosaccharide Activity-Based Inactivators for Endoglycanases: A Case Study on alpha-1,6 Mannanases.; Chemistry, 27:9519-9523, 2021; PubMed: 33878235; DOI: 10.1002/chem.202101255

実験手法

X-RAY DIFFRACTION (1.4 Å)