7NJ3
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8196 core
Summary for 7NJ3
Entry DOI | 10.2210/pdb7nj3/pdb |
EMDB information | 12371 |
Descriptor | Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... (6 entities in total) |
Functional Keywords | influenza, rna polymerase, h1n1, 1918, viral protein, nanobody |
Biological source | Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) More |
Total number of polymer chains | 6 |
Total formula weight | 296417.76 |
Authors | Keown, J.R.,Carrique, L.,Fodor, E.,Grimes, J.M. (deposition date: 2021-02-15, release date: 2021-12-01, Last modification date: 2024-10-09) |
Primary citation | Keown, J.R.,Zhu, Z.,Carrique, L.,Fan, H.,Walker, A.P.,Serna Martin, I.,Pardon, E.,Steyaert, J.,Fodor, E.,Grimes, J.M. Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13:251-251, 2022 Cited by PubMed: 35017564DOI: 10.1038/s41467-021-27950-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.48 Å) |
Structure validation
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