7NGD

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound

7NGD の概要

• エントリーDOI: 10.2210/pdb7ngd/pdb
• 分子名称: HTH-type transcriptional regulator EthR, 4-methyl-~{N}-(4-phenylbutyl)piperidine-1-carboxamide (3 entities in total)
• 機能のキーワード: ethr, tuberculosis, inhibition, transcription
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24056.11

構造登録者

Tomlinson, C.W.E.,Tatum, N.J.,Pohl, E. (登録日: 2021-02-09, 公開日: 2022-02-23, 最終更新日: 2024-01-31)

• 主引用文献: Tatum, N.J.,Tomlinson, C.W.E.,Frita, R.,Bennett, R.,Baulard, A.R.,Pohl, E.,Kitching, M.O.; Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization; To Be Published,

実験手法

X-RAY DIFFRACTION (1.47 Å)