7N7G
Crystal Structure of FosB from Enterococcus faecium with Fosfomycin
Summary for 7N7G
Entry DOI | 10.2210/pdb7n7g/pdb |
Descriptor | Metallothiol transferase FosB, MANGANESE (II) ION, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | fosfomycin, antibiotic resistance, thiol-transferase, antibiotic, dimer, transferase-antibiotic complex, transferase/antibiotic |
Biological source | Enterococcus faecium |
Total number of polymer chains | 2 |
Total formula weight | 33641.24 |
Authors | Shay, M.R.,Simmons, Z.,Thompson, M.K. (deposition date: 2021-06-10, release date: 2022-07-27, Last modification date: 2023-10-18) |
Primary citation | Wiltsie, V.,Travis, S.,Shay, M.R.,Simmons, Z.,Frantom, P.,Thompson, M.K. Structural and functional characterization of fosfomycin resistance conferred by FosB from Enterococcus faecium. Protein Sci., 31:580-590, 2022 Cited by PubMed: 34882867DOI: 10.1002/pro.4253 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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