7N7G

Crystal Structure of FosB from Enterococcus faecium with Fosfomycin

Summary for 7N7G

• Entry DOI: 10.2210/pdb7n7g/pdb
• Descriptor: Metallothiol transferase FosB, MANGANESE (II) ION, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: fosfomycin, antibiotic resistance, thiol-transferase, antibiotic, dimer, transferase-antibiotic complex, transferase/antibiotic
• Biological source: Enterococcus faecium
• Total number of polymer chains: 2
• Total formula weight: 33641.24

Authors

Shay, M.R.,Simmons, Z.,Thompson, M.K. (deposition date: 2021-06-10, release date: 2022-07-27, Last modification date: 2023-10-18)

• Primary citation: Wiltsie, V.,Travis, S.,Shay, M.R.,Simmons, Z.,Frantom, P.,Thompson, M.K.; Structural and functional characterization of fosfomycin resistance conferred by FosB from Enterococcus faecium.; Protein Sci., 31:580-590, 2022; PubMed: 34882867; DOI: 10.1002/pro.4253

Experimental method

X-RAY DIFFRACTION (2 Å)