7N63

X-ray structure of HCAN_0200, an aminotransferase from Helicobacter canadensis in complex with its external aldimine

Summary for 7N63

• Entry DOI: 10.2210/pdb7n63/pdb
• Descriptor: Putative aminotransferase, (2R,3R,4S,5S,6R)-3,5-dihydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: aminotransferase, pyridoxyl phosphate, external aldimine, transferase
• Biological source: Helicobacter canadensis MIT 98-5491
• Total number of polymer chains: 1
• Total formula weight: 43648.42

Authors

Griffiths, W.A.,Heisdorf, C.J.,Thoden, J.B.,Holden, H.M. (deposition date: 2021-06-07, release date: 2021-06-23, Last modification date: 2023-10-18)

• Primary citation: Heisdorf, C.J.,Griffiths, W.A.,Thoden, J.B.,Holden, H.M.; Investigation of the enzymes required for the biosynthesis of an unusual formylated sugar in the emerging human pathogen Helicobacter canadensis.; Protein Sci., 30:2144-2160, 2021; PubMed: 34379357; DOI: 10.1002/pro.4169

Experimental method

X-RAY DIFFRACTION (1.4 Å)