7N63

X-ray structure of HCAN_0200, an aminotransferase from Helicobacter canadensis in complex with its external aldimine

7N63 の概要

• エントリーDOI: 10.2210/pdb7n63/pdb
• 分子名称: Putative aminotransferase, (2R,3R,4S,5S,6R)-3,5-dihydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate, MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: aminotransferase, pyridoxyl phosphate, external aldimine, transferase
• 由来する生物種: Helicobacter canadensis MIT 98-5491
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43648.42

構造登録者

Griffiths, W.A.,Heisdorf, C.J.,Thoden, J.B.,Holden, H.M. (登録日: 2021-06-07, 公開日: 2021-06-23, 最終更新日: 2023-10-18)

• 主引用文献: Heisdorf, C.J.,Griffiths, W.A.,Thoden, J.B.,Holden, H.M.; Investigation of the enzymes required for the biosynthesis of an unusual formylated sugar in the emerging human pathogen Helicobacter canadensis.; Protein Sci., 30:2144-2160, 2021; PubMed: 34379357; DOI: 10.1002/pro.4169

実験手法

X-RAY DIFFRACTION (1.4 Å)