7N4Y

The structure of bovine thyroglobulin with iodinated tyrosines

Summary for 7N4Y

• Entry DOI: 10.2210/pdb7n4y/pdb
• EMDB information: 24181
• Descriptor: Thyroglobulin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: thyroid hormone synthesis, hormone
• Biological source: Bos indicus x Bos taurus (Hybrid cattle)
• Total number of polymer chains: 2
• Total formula weight: 612399.54

Authors

Kim, K.,Clarke, O.B. (deposition date: 2021-06-04, release date: 2021-11-10, Last modification date: 2023-11-15)

• Primary citation: Kim, K.,Kopylov, M.,Bobe, D.,Kelley, K.,Eng, E.T.,Arvan, P.,Clarke, O.B.; The structure of natively iodinated bovine thyroglobulin.; Acta Crystallogr D Struct Biol, 77:1451-1459, 2021; PubMed: 34726172; DOI: 10.1107/S2059798321010056

Experimental method

ELECTRON MICROSCOPY (2.61 Å)