7N3Z

Crystal Structure of Saccharomyces cerevisiae Apn2 Catalytic Domain

Summary for 7N3Z

Entry DOI	10.2210/pdb7n3z/pdb
Related	7N3Y
Descriptor	DNA-(apurinic or apyrimidinic site) endonuclease 2, MAGNESIUM ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	nuclease, dna repair, eep fold, ape2 homolog, hydrolase
Biological source	Saccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains	1
Total formula weight	47445.89
Authors	Wojtaszek, J.L.,Wallace, B.D.,Williams, R.S. (deposition date: 2021-06-02, release date: 2022-09-28, Last modification date: 2023-10-18)
Primary citation	Williams, J.S.,Wojtaszek, J.L.,Appel, D.C.,Krahn, J.,Wallace, B.D.,Walsh, E.,Kunkel, T.A.,Williams, R.S. Molecular basis for processing of topoisomerase 1-triggered DNA damage by Apn2/APE2. Cell Rep, 41:111448-111448, 2022 Cited by PubMed: 36198268 DOI: 10.1016/j.celrep.2022.111448 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation