7N3K

Oridonin-bound SARS-CoV-2 Nsp9

7N3K の概要

• エントリーDOI: 10.2210/pdb7n3k/pdb
• 分子名称: Non-structural protein 9, (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one, SULFATE ION (3 entities in total)
• 機能のキーワード: sars-cov-2, nsp9, rna binding complex, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 120056.98

構造登録者

Littler, D.R.,Gully, B.S.,Rossjohn, J. (登録日: 2021-06-01, 公開日: 2021-10-27, 最終更新日: 2023-10-18)

• 主引用文献: Littler, D.R.,Liu, M.,McAuley, J.L.,Lowery, S.A.,Illing, P.T.,Gully, B.S.,Purcell, A.W.,Chandrashekaran, I.R.,Perlman, S.,Purcell, D.F.J.,Quinn, R.J.,Rossjohn, J.; A natural product compound inhibits coronaviral replication in vitro by binding to the conserved Nsp9 SARS-CoV-2 protein.; J.Biol.Chem., 297:101362-101362, 2021; PubMed: 34756886; DOI: 10.1016/j.jbc.2021.101362

実験手法

X-RAY DIFFRACTION (3 Å)