7N38

Crystal structure of 5-site deamidated variant of human gamma(S)-crystallin

Summary for 7N38

Entry DOI	10.2210/pdb7n38/pdb
Descriptor	Gamma-crystallin S, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	structural protein, crystallin, human crystallin, gamma(s) crystallin, eye lens protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	21198.10
Authors	Norton-Baker, B.,Mehrabi, P.,Martin, R.W. (deposition date: 2021-05-31, release date: 2022-03-23, Last modification date: 2023-10-18)
Primary citation	Norton-Baker, B.,Mehrabi, P.,Kwok, A.O.,Roskamp, K.W.,Rocha, M.A.,Sprague-Piercy, M.A.,von Stetten, D.,Miller, R.J.D.,Martin, R.W. Deamidation of the human eye lens protein gamma S-crystallin accelerates oxidative aging. Structure, 30:763-776.e4, 2022 Cited by PubMed: 35338852 DOI: 10.1016/j.str.2022.03.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.22 Å)

Structure validation