7N33

SARS-CoV-2 Nsp15 endoribonuclease pre-cleavage state

Summary for 7N33

• Entry DOI: 10.2210/pdb7n33/pdb
• Related: 7N06
• EMDB information: 24101 24137
• Descriptor: Uridylate-specific endoribonuclease, RNA (5'-R(*A)-D(*(UFT))-R(P*A)-3') (2 entities in total)
• Functional Keywords: endoribonuclease, viral protein, viral protein-rna complex, viral protein/rna
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 12
• Total formula weight: 248667.97

Authors

Frazier, M.N.,Dillard, L.B.,Krahn, J.M.,Stanley, R.E. (deposition date: 2021-05-31, release date: 2021-06-09, Last modification date: 2024-05-29)

• Primary citation: Frazier, M.N.,Dillard, L.B.,Krahn, J.M.,Perera, L.,Williams, J.G.,Wilson, I.M.,Stewart, Z.D.,Pillon, M.C.,Deterding, L.J.,Borgnia, M.J.,Stanley, R.E.; Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U.; Nucleic Acids Res., 49:10136-10149, 2021; PubMed: 34403466; DOI: 10.1093/nar/gkab719

Experimental method

ELECTRON MICROSCOPY (2.5 Å)