7MZT
Borrelia burgdorferi BBK32-C in complex with an autolytic fragment of human C1r at 4.1A
Summary for 7MZT
| Entry DOI | 10.2210/pdb7mzt/pdb |
| Descriptor | Complement C1r subcomponent heavy chain, Complement C1r subcomponent light chain, Fibronectin-binding protein BBK32, ... (4 entities in total) |
| Functional Keywords | lyme disease spirochete, borrelia burgdorferi, complement system, classical pathway, protease inhibitor, protein binding |
| Biological source | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680) More |
| Total number of polymer chains | 3 |
| Total formula weight | 63479.99 |
| Authors | Garcia, B.L. (deposition date: 2021-05-24, release date: 2021-09-29, Last modification date: 2023-10-18) |
| Primary citation | Garrigues, R.J.,Powell-Pierce, A.D.,Hammel, M.,Skare, J.T.,Garcia, B.L. A Structural Basis for Inhibition of the Complement Initiator Protease C1r by Lyme Disease Spirochetes. J Immunol., 207:2856-2867, 2021 Cited by PubMed: 34759015DOI: 10.4049/jimmunol.2100815 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (4.07 Å) |
Structure validation
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