7MZT

Borrelia burgdorferi BBK32-C in complex with an autolytic fragment of human C1r at 4.1A

7MZT の概要

• エントリーDOI: 10.2210/pdb7mzt/pdb
• 分子名称: Complement C1r subcomponent heavy chain, Complement C1r subcomponent light chain, Fibronectin-binding protein BBK32, ... (4 entities in total)
• 機能のキーワード: lyme disease spirochete, borrelia burgdorferi, complement system, classical pathway, protease inhibitor, protein binding
• 由来する生物種: Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 63479.99

構造登録者

Garcia, B.L. (登録日: 2021-05-24, 公開日: 2021-09-29, 最終更新日: 2023-10-18)

• 主引用文献: Garrigues, R.J.,Powell-Pierce, A.D.,Hammel, M.,Skare, J.T.,Garcia, B.L.; A Structural Basis for Inhibition of the Complement Initiator Protease C1r by Lyme Disease Spirochetes.; J Immunol., 207:2856-2867, 2021; PubMed: 34759015; DOI: 10.4049/jimmunol.2100815

実験手法

X-RAY DIFFRACTION (4.07 Å)