7MTS

CryoEM Structure of mGlu2 - Gi Complex

7MTS の概要

• エントリーDOI: 10.2210/pdb7mts/pdb
• EMDBエントリー: 23996
• 分子名称: Metabotropic glutamate receptor 2, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total)
• 機能のキーワード: metabotropic glutamate receptor 2 (mglu2) (mglur2), family c g protein-coupled receptor (gpcr), heterotrimeric g protein, cryoem structure, membrane protein, membrane protein-signaling protein complex, membrane protein/signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 274646.03

構造登録者

Seven, A.B.,Barros-Alvarez, X.,Skiniotis, G. (登録日: 2021-05-13, 公開日: 2021-07-07, 最終更新日: 2021-07-28)

• 主引用文献: Seven, A.B.,Barros-Alvarez, X.,de Lapeyriere, M.,Papasergi-Scott, M.M.,Robertson, M.J.,Zhang, C.,Nwokonko, R.M.,Gao, Y.,Meyerowitz, J.G.,Rocher, J.P.,Schelshorn, D.,Kobilka, B.K.,Mathiesen, J.M.,Skiniotis, G.; G-protein activation by a metabotropic glutamate receptor.; Nature, 595:450-454, 2021; PubMed: 34194039; DOI: 10.1038/s41586-021-03680-3

実験手法

ELECTRON MICROSCOPY (3.2 Å)