7MPD

Structure of SsoPTP bound to 2-chloroethylsulfonate

7MPD の概要

• エントリーDOI: 10.2210/pdb7mpd/pdb
• 分子名称: SsoPTP, 2-chloroethane-1-sulfonic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
• 機能のキーワード: protein tyrosine phosphatase, 2-chloroethylsuflonate, ssoptp, hydrolase
• 由来する生物種: Saccharolobus solfataricus (Sulfolobus solfataricus)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18816.05

構造登録者

Pinkston, J.A.,Olsen, K.J.,Hengge, A.C.,Johnson, S.J. (登録日: 2021-05-04, 公開日: 2021-09-22, 最終更新日: 2023-10-18)

• 主引用文献: Pinkston, J.,Jo, J.,Olsen, K.J.,Comer, D.,Glaittli, C.A.,Loria, J.P.,Johnson, S.J.,Hengge, A.C.; Significant Loop Motions in the SsoPTP Protein Tyrosine Phosphatase Allow for Dual General Acid Functionality.; Biochemistry, 60:2888-2901, 2021; PubMed: 34496202; DOI: 10.1021/acs.biochem.1c00365

実験手法

X-RAY DIFFRACTION (1.05 Å)