7MPB

SARS Coronavirus-2 Main Protease 3CL-pro binding Ascorbate

7MPB の概要

• エントリーDOI: 10.2210/pdb7mpb/pdb
• 分子名称: 3C-like proteinase, ASCORBIC ACID, TRIFLUOROETHANOL, ... (4 entities in total)
• 機能のキーワード: sars coronavirus-2 main protease, 3cl-pro, 3clp, sars-cov-2 main protease, viral protein, hydrolase
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 70169.49

構造登録者

Pandey, S.,Malla, T.N.,Stojkovic, E.A.,Schmidt, M. (登録日: 2021-05-04, 公開日: 2021-05-12, 最終更新日: 2023-10-18)

• 主引用文献: Malla, T.N.,Pandey, S.,Poudyal, I.,Aldama, L.,Feliz, D.,Noda, M.,Phillips, G.N.,Stojkovic, E.A.,Schmidt, M.; Vitamin C inhibits SARS coronavirus-2 main protease essential for viral replication; Biorxiv, 2021; DOI: 10.1101/2021.05.02.442358

実験手法

X-RAY DIFFRACTION (2.3 Å)