7MOL

Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) in complex with phosphate in conformation B (Pi(B))

7MOL の概要

• エントリーDOI: 10.2210/pdb7mol/pdb
• 分子名称: Tyrosine-protein phosphatase DSP1, PHOSPHATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
• 機能のキーワード: inositol, inositol pyrophosphate, transferase, hydrolase, cell-signaling, phosphatase, substrate recognition, reaction mechanism, intermediate, phosphate, metaphosphate, molecular dynamic simulation, self-activation, catalytic water
• 由来する生物種: Arabidopsis thaliana (Mouse-ear cress)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 39984.22

構造登録者

Wang, H.,Shears, S.B. (登録日: 2021-05-01, 公開日: 2022-03-02, 最終更新日: 2022-05-11)

• 主引用文献: Wang, H.,Perera, L.,Jork, N.,Zong, G.,Riley, A.M.,Potter, B.V.L.,Jessen, H.J.,Shears, S.B.; A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.; Nat Commun, 13:2231-2231, 2022; PubMed: 35468885; DOI: 10.1038/s41467-022-29673-y

実験手法

X-RAY DIFFRACTION (1.9 Å)