7MLH
Crystal structure of human IgE (2F10) in complex with Der p 2.0103
Summary for 7MLH
Entry DOI | 10.2210/pdb7mlh/pdb |
Descriptor | IgE Light Chain, Der p 2 variant 3, IgE Heavy chain, ... (6 entities in total) |
Functional Keywords | allergy, ige, house dust mites, antibody, allergen, allergen-immune system complex, allergen/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 124129.10 |
Authors | Khatri, K.,Kapingidza, A.B.,Richardson, C.M.,Vailes, L.D.,Wunschmann, S.,Dolamore, C.,Chapman, M.D.,Smith, S.A.,Pomes, A.,Chruszcz, M. (deposition date: 2021-04-28, release date: 2022-05-04, Last modification date: 2023-10-18) |
Primary citation | Khatri, K.,Richardson, C.M.,Glesner, J.,Kapingidza, A.B.,Mueller, G.A.,Zhang, J.,Dolamore, C.,Vailes, L.D.,Wunschmann, S.,Peebles Jr., R.S.,Chapman, M.D.,Smith, S.A.,Chruszcz, M.,Pomes, A. Human IgE monoclonal antibody recognition of mite allergen Der p 2 defines structural basis of an epitope for IgE cross-linking and anaphylaxis in vivo. Pnas Nexus, 1:pgac054-pgac054, 2022 Cited by PubMed: 35799831DOI: 10.1093/pnasnexus/pgac054 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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