7MLH

Crystal structure of human IgE (2F10) in complex with Der p 2.0103

7MLH の概要

• エントリーDOI: 10.2210/pdb7mlh/pdb
• 分子名称: IgE Light Chain, Der p 2 variant 3, IgE Heavy chain, ... (6 entities in total)
• 機能のキーワード: allergy, ige, house dust mites, antibody, allergen, allergen-immune system complex, allergen/immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 124129.10

構造登録者

Khatri, K.,Kapingidza, A.B.,Richardson, C.M.,Vailes, L.D.,Wunschmann, S.,Dolamore, C.,Chapman, M.D.,Smith, S.A.,Pomes, A.,Chruszcz, M. (登録日: 2021-04-28, 公開日: 2022-05-04, 最終更新日: 2023-10-18)

• 主引用文献: Khatri, K.,Richardson, C.M.,Glesner, J.,Kapingidza, A.B.,Mueller, G.A.,Zhang, J.,Dolamore, C.,Vailes, L.D.,Wunschmann, S.,Peebles Jr., R.S.,Chapman, M.D.,Smith, S.A.,Chruszcz, M.,Pomes, A.; Human IgE monoclonal antibody recognition of mite allergen Der p 2 defines structural basis of an epitope for IgE cross-linking and anaphylaxis in vivo.; Pnas Nexus, 1:pgac054-pgac054, 2022; PubMed: 35799831; DOI: 10.1093/pnasnexus/pgac054

実験手法

X-RAY DIFFRACTION (2.1 Å)