7MJU

Crystal structure of human AF10 PZP bound to histone H3 tail

Summary for 7MJU

• Entry DOI: 10.2210/pdb7mju/pdb
• Descriptor: Histone H3.1,Protein AF-10, ZINC ION (3 entities in total)
• Functional Keywords: histone binding leukemia, peptide binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 22936.81

Authors

Klein, B.J.,Kutateladze, T.G. (deposition date: 2021-04-20, release date: 2021-08-04, Last modification date: 2024-05-22)

• Primary citation: Klein, B.J.,Deshpande, A.,Cox, K.L.,Xuan, F.,Zandian, M.,Barbosa, K.,Khanal, S.,Tong, Q.,Zhang, Y.,Zhang, P.,Sinha, A.,Bohlander, S.K.,Shi, X.,Wen, H.,Poirier, M.G.,Deshpande, A.J.,Kutateladze, T.G.; The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations.; Nat Commun, 12:4130-4130, 2021; PubMed: 34226546; DOI: 10.1038/s41467-021-24418-9

Experimental method

X-RAY DIFFRACTION (2.1 Å)