7MJ1

LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with NAD

7MJ1 の概要

• エントリーDOI: 10.2210/pdb7mj1/pdb
• 分子名称: Pyridinium-3,5-biscarboxylic acid mononucleotide synthase, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
• 機能のキーワード: carboxylase, hydrolase, lyase (carbon-carbon)
• 由来する生物種: Lactobacillus plantarum
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 160487.45

構造登録者

Chatterjee, S.,Rankin, J.A.,Lagishetty, S.,Hu, J.,Hausinger, R.P. (登録日: 2021-04-19, 公開日: 2021-09-29, 最終更新日: 2023-10-18)

• 主引用文献: Rankin, J.A.,Chatterjee, S.,Tariq, Z.,Lagishetty, S.,Desguin, B.,Hu, J.,Hausinger, R.P.; The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 34548397; DOI: 10.1073/pnas.2106202118

実験手法

X-RAY DIFFRACTION (3.402 Å)