7MIE

Crystal structure of the Borreliella burgdorferi PlzA protein in complex with c-di-GMP

Summary for 7MIE

• Entry DOI: 10.2210/pdb7mie/pdb
• Descriptor: PlzA, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: tick-borne pathogens, borreliella burgdorferi, pilz domain, c-di-gmp-binding receptor signaling, signaling protein
• Biological source: Borrelia burgdorferi
• Total number of polymer chains: 1
• Total formula weight: 33587.14

Authors

Davies, C.,Singh, A. (deposition date: 2021-04-16, release date: 2021-06-30, Last modification date: 2024-05-22)

• Primary citation: Singh, A.,Izac, J.R.,Schuler, E.J.A.,Patel, D.T.,Davies, C.,Marconi, R.T.; High-resolution crystal structure of the Borreliella burgdorferi PlzA protein in complex with c-di-GMP: new insights into the interaction of c-di-GMP with the novel xPilZ domain.; Pathog Dis, 79:-, 2021; PubMed: 34117751; DOI: 10.1093/femspd/ftab030

Experimental method

X-RAY DIFFRACTION (1.6 Å)