7MHQ

Ensemble refinement structure of SARS-CoV-2 main protease (Mpro) at 310 K

Summary for 7MHQ

• Entry DOI: 10.2210/pdb7mhq/pdb
• Related: 7MHF 7MHG 7MHH 7MHI 7MHJ 7MHK 7MHL 7MHM 7MHN 7MHO 7MHP
• Descriptor: 3C-like proteinase, DIMETHYL SULFOXIDE, ZINC ION, ... (4 entities in total)
• Functional Keywords: sars-cov-2, coronavirus, main protease, 3clpro, mpro, hydrolase, ensemble refinement, temperature series, temperature, multitemperature
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 34047.22

Authors

Ebrahim, A.,Riley, B.T.,Kumaran, D.,Andi, B.,Fuchs, M.R.,McSweeney, S.,Keedy, D.A. (deposition date: 2021-04-15, release date: 2021-05-12, Last modification date: 2023-10-18)

• Primary citation: Ebrahim, A.,Riley, B.T.,Kumaran, D.,Andi, B.,Fuchs, M.R.,McSweeney, S.,Keedy, D.A.; The temperature-dependent conformational ensemble of SARS-CoV-2 main protease (M pro ); Iucrj, 9:682-694, 2022; DOI: 10.1107/S2052252522007497

Experimental method

X-RAY DIFFRACTION (1.9601 Å)