7MF8
Crystal structure of antibody 10E8v4-P100fA Fab in space group P6422
Summary for 7MF8
Entry DOI | 10.2210/pdb7mf8/pdb |
Descriptor | Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain (3 entities in total) |
Functional Keywords | monoclonal antibody 10e8, mper, cis-trans isomerization, size-exclusion chromatography, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 48062.43 |
Authors | Kwon, Y.D.,Kwong, P.D. (deposition date: 2021-04-08, release date: 2021-07-14, Last modification date: 2023-10-18) |
Primary citation | Do Kwon, Y.,Wang, X.E.,Bender, M.F.,Yang, R.,Li, Y.,McKee, K.,Rawi, R.,O'Dell, S.,Schneck, N.A.,Shaddeau, A.,Zhang, B.,Arnold, F.J.,Connors, M.,Doria-Rose, N.A.,Kwong, P.D.,Lei, Q.P. Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography. Antibodies, 10:-, 2021 Cited by PubMed: 34200826DOI: 10.3390/antib10020023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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